7 Best Drugstore Retinols We Tested 2026, Approved by Dermatologists
- Pros: Non-comedogenic; fragrance-free
- Cons: You’ll likely need to build up tolerance (start 2-3 nights/week)
If you want a drugstore retinol that feels hard to mess up, this is it. Dr. Garshick recommends this encapsulated retinol serum as one of her favorites because it’s designed to release slowly, which can make it easier to tolerate. “It’s formulated as an encapsulated (or slow-released and deep penetrating) retinol to reduce the appearance of fine lines and dullness. It also incorporates niacinamide, hyaluronic acid, and ceramides to strengthen the skin barrier and deliver all-day hydration,” she says. In other words, you’re getting retinol plus a supporting cast that helps buffer the dryness and irritation people often associate with starting a retinoid.
In our testing, the texture lands somewhere between a serum and a light moisturizer, and it layered easily under a basic night cream. Several testers noted it felt gentle on skin that’s prone to redness, and over time, it helped skin look smoother, brighter, and more even.
“It has a whipped, thick formula that dries down nicely and has never (in the slightest) made me irritated or red. The formulation is potent, instantly clarifying congested skin and areas riddled with dark spots and acne scars—a lot of which I have around my nose and on my chin. After using this every few nights for the past three months, my skin looks brighter, even-toned, and softer than ever. I’m obsessed!”
“This is a great beginner-friendly dark-spot correcting retinol serum. It was actually the first retinol product I ever used in my late 20s, and I continue to use it now in my 30s. I’ve gone through three bottles. The serum-moisturizer hybrid is very lightweight and absorbs nicely on the skin,” she says. “I’ve never had a bad reaction on my combination skin, and I notice it feels a lot smoother and more radiant after consistent use. As always, make sure to follow the instructions so you don’t overuse it,” she reminds users.
- Skin types: Sensitive skin types, acne-prone skin
- Key ingredient(s): Retinol, licorice root, niacinamide, ceramides
- Size: 1 fl. oz.
Best for Sensitive Skin: The Ordinary Retinol 0.5% in Squalane
Original video from Alanna Martine Kilkeary testing The Ordinary Retinol 0.5% in Squalane
- Pros: Lightweight; very moisturizing
- Cons: A little oily and it doesn’t have the best smell
